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Drugs which may cause folate deficiency include phenytoin, isoniazid, primidone, barbiturates, oral contraceptives, ethanol, sulfasalazine, cycloserine, glutethamide, methotrexate, pyrimethamine, trimethoprim and triamterene.
Zinc interferes with captopril, absorption of Tetracycline antibiotics, Thiazide & Potassium-sparing diuretics. It decreases the absorption and effectiveness of Fluoroquinolones antibiotics (Cipro, Levaquin), Iron supplement.
Acid Pump Inhibitors: (Lansoprazole, omeprazole, pantoprazole, rabeprazole).
Antacids: Aluminum-or-magnesium-containing antacids.
Bisphosphonates (alendronate, etidronate, risedronate).
H2 Blockers (cimetidine, famotidine, nizatidine, ranitidine).
Penicillamine.
Quinolones (ciprofloxacin, gatifloxacin, levofloxacin, lomefloxacin, moxifloxacin, norfloxacin, ofloxacin, sparfloxacin, trovafloxacin).
